nguyen dermatology

Cosmetic Dermatology services address the aesthetic concerns of your skin such as wrinkles, sagging skin, uneven tone, texture changes, and treatment of benign growths that can occur with the normal aging process. These services are rarely covered by insurance. 

 

We offer a range of cosmetic services including fillers such as Restylane, Radiesse, Belotero, botulinum toxin,  Laser hair removal, Intense pulse light Lumecca, Fractora skin rejuvenation, Fractora scar treatment for hypertrophic scarring, High Intensity Focused Ultrasound (HIFU) for facial firming and rejuvenation, Platelet Rich Plasma (PRP) for hair loss, Platelet Rich Fibrin (PRF), PRP and PRF microneedling facial, PRP and PRF injections, Microneedling, HydraGLOW facial, HydraGLOW acne facial, treatments for hyperpigmentation / melasma, skin firming and cellulite treatment with Velashape, Dermaplaning, chemical masks and peels. Schedule to meet our aesthetician for a free consult.  Follow us on Instagram and Facebook or click the link on this page to see all our before and afters.   

 

We now offer PRF. 

 

WHAT IS THE DIFFERENCE BETWEEEN PRF vs PRP?  (PLATELET-RICH FIBRIN vs PLATELET-RICH PLASMA)

 

PRF and PRP are blood concentrate therapy.  Both utilize our own blood to get the healing response that occurs naturally when platelets are activated during the injury process.  Platelets obtained from our peripheral blood act as an autologous source of growth factors.  

 

Why is PRF better than PRP?  

• PRF is a fibrin matrix in which platelet cytokines, growth factors and cells are trapped and kept alive for longer.

• PRF has white blood cells, fibrin scaffold, and mesenchymal stem cells which are not found in PRP.   

• PRF has higher concentration of platelets - more healing power.  

  • PRP has 2 - 5 times the level platelets found in normal blood. 

  • PRF has 10 times the platelet concentration found in normal blood.

• PRF has leukocytes (white blood cells) -  important producers of growth factors.  

• PRF has fibrin matrix that allows for slow release of growth factors and cytokines to bathe the tissue measured in days vs hours. 

 

Research is showing that PRF is more effective because it has higher concentrations of platelets, as well as a higher concentration of white blood cells and stem cells.  To create PRF the blood is spun at a lower speed so that the layers of the blood do not separate out as distinctly. This allows some of the white blood cells and stem cells to remain within the platelet layer, instead of being separated. This gives PRF more healing factors than PRP. Plus, the lower centrifuge speed causes less trauma with the individual cells involved.

 

Another difference is the final concentration of platelets in PRP and PRF. 

Also, PRF does not contain any additives, whereas an anticoagulant is used during the processing of the blood when making PRP. Without the anticoagulant, PRF takes the natural fibrinogen within our blood and it is converted to fibrin by thrombin in the early stages of clot formation. This creates a spongy fibrin matrix that activates the platelets that acts as a scaffolding to keep the growth factors and stem cells in the area they are injected, keeping them from diffusing, which can happen with PRP.

 

1. Naik B, Karunakar P, Jayadev M, Marshal VR. Role of Platelet rich fibrin in wound healing: A critical review. J Conserv Dent. 2013;16(4):284-293. doi:10.4103/0972-0707.114344

2. New Frontiers in Skin Rejuvenation, Including Stem Cells and Autologous Therapies.  Aunna Pourang, M.Da., Helena Rockwell, B.Scb., Kian Karimi, M.Dc. | Facial Plast Surg Clin | 2020

Kian Karimi, M.D., Helena Rockwell, B.Sc. The Benefits of PlateletRich Fibrin